Indian agent and interpreter for the province of Pennsylvania. A principal agent and architect of Pennsylvania’s Indian policy.

Emigrated from Germany to New York (1710). Wintered with the Indian chief Quagnant, and learned the Maqua (Mohawk) tongue and Indian customs (1713-14).

Served as an interpreter at the Indian village near Schoharie (1719-29). Settled on the Tulpehocken in Pennsylvania (1729).

Following a religious conversion, he moved his family to Ephrata and joined a cloister under the name of Brother Enoch (1735).

Justice of the peace for Lancaster County (1741). Severed his ties with the cloister at Ephrata (1743). Traveled to Onondago to aid in a Moravian mission to the Indians (1743). Joined the Lutheran Church (1747).

William Franklin accompanied him to a conference with the Ohio Indians at Logstown (1748). A justice of the peace (1752) and the first president-judge of Berks County (1752-60). Present at the Carlisle treaty sessions (1753). Commissioned colonel in the Berks County regiment (1755).

Settled in Reading (1755). Joined the Reformed Church.

Born near Herrenberg, Württemberg, Germany. Father of Samuel Weiser.